Table 4. Outcome for the 192 women in the HPV group if triaged by post-colposcopy HPV mRNA only.
| HPV mRNA result | Outcome | % | 95% CI | |||
| CIN2+1) | <CIN22) | Total3) | Sensitivity | 89.1 | 80.1, 98.1 | |
| Positive | 41 | 11 | 52 | Specificity | 92.5 | 88.2, 96.7 |
| Negative | 5 | 135 | 140 | PPV | 78.8 | 67.7, 89.9 |
| Total | 46 | 146 | 192 | NPV | 96.4 | 93.3, 99.5 |
1)
Prevalence CIN2+ 24.0% (95% CI: 17.9–30.0).
2)
<CIN2 includes women with a histological diagnosis of CIN1 or CIN0 and women referred back to screening because of two normal post-colposcopy smears or normal LBC and a negative HPV result.
3)
Chi square = 117.9, p<0.001.