(a) Typical configuration of the membrane model developed by Drouffe and co-workers (α=η=1, T=1.6ϵ). A flat sheet of 256 particles with parallel orientation vectors was used as the initial configuration. This structure dissolves quickly into a disordered collection of small clusters. (b) Final configuration of a trajectory starting from the same initial state, but employing an alternative parameter set (α=1, η=−1, and T=0.5ϵ). The initially flat sheet remains stable, and closes to form a vesicle.