Table 1.
Diagnostic test results for the three ROI analysis groups: All ROIs, H&E + ROIs and H&E − ROIs.
| Type of imaging contrast |
|||||||||
|---|---|---|---|---|---|---|---|---|---|
| All ROIs |
H&E + ROIs |
H&E − ROIs |
|||||||
| Diagnostic tests | PpIX | T1W+Gd | T2 map | PpIX | T1W+Gd | T2 map | PpIX | T1W+Gd | T2 map |
| AUCa | 0.95 | 0.69 | 0.84 | 1 | 0.88 | 0.91 | 0.91 | 0.55 | 0.79 |
| (±0.04) | (±0.07) | (±0.05) | (±0) | (±0.05) | (±0.05) | (±0.05) | (±0.09) | (±0.07) | |
| Sensitivity | 0.89 | 0.28 | 0.64 | 1 | 0.57 | 0.71 | 0.82 | 0.09 | 0.59 |
| Specificity | 1 | 1 | 0.85 | 1 | 1 | 0.85 | 1 | 1 | 0.85 |
| PPVa | 1 | 1 | 0.81 | 1 | 1 | 0.82 | 1 | 1 | 0.79 |
| NPVa | 0.90 | 0.58 | 0.70 | 1 | 0.70 | 0.75 | 0.85 | 0.52 | 0.67 |
| Diag. Acc.a | 0.94 | 0.64 | 0.74 | 1 | 0.79 | 0.78 | 0.91 | 0.55 | 0.72 |
a
AUC = area under the curve (refers to ROC curves in Figure 3), PPV = positive predictive value, NPV = negative predictive value, Diag. Acc. = diagnostic accuracy.