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. Author manuscript; available in PMC: 2013 Jan 1.
Published in final edited form as: Lung Cancer. 2011 Jun 12;75(1):15–23. doi: 10.1016/j.lungcan.2011.05.017

Fig. 4. Associations between retinoic acid and α-tocopherol (AT) levels, squamous metaplasia, and c-Jun and cyclin D1 expressions in the lungs of ferrets after 6 weeks of smoke exposure and with or without AT+AA supplementation.

Fig. 4

(A) α-Tocopherol levels by squamous metaplasia, *Significant difference between smoke-exposed lungs without vs. those with squamous metaplasia (p = 0.036 after transformation, Student’s t test); (B) Pair-wise scatter plot for the correlation between c-Jun expression and α-tocopherol levels in smoke-exposed lungs; (C) Pair-wise scatter plot for the correlation between c-Jun and cyclin D1 expressions in smoke-exposed lungs; (D) Levels of retinoic acid, α-tocopherol, and c-Jun protein expression in the lungs of ferrets from the various treatment groups. Abbreviations: same as in Figure 3, r = correlation coefficient.