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. Author manuscript; available in PMC: 2012 Oct 1.
Published in final edited form as: J Neurochem. 2011 Sep 20;119(2):303–313. doi: 10.1111/j.1471-4159.2011.07428.x

Fig. 5.

Fig. 5

Nerve agents exposure dysregulates Cdk5 activity in vivo. Effects of systemic exposure to PB, DEET, and DFP on p25 generation and Cdk5-dependent phosphorylation of P-T75 DARPP-32 in mouse striatum (a and b). Representative blots from tissue taken 2 or 6 h after treatments are shown above quantification. Effects of systemic exposure to PB, DEET, and DFP on p25 generation in hippocampus (c and d). *p=0.0108, **p=0.0045, ***p=0.0004, Student’s t-test, for a, n=3-4. *p=0.0102, #p<0.0001, Student’s t-test, for b, n=3-4.