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. Author manuscript; available in PMC: 2012 Oct 13.
Published in final edited form as: J Med Chem. 2011 Sep 9;54(19):6647–6656. doi: 10.1021/jm200521a

Figure 2.

Figure 2

Reductive activation of BP prodrug 14. (a) prodrug 14 prior to reduction; (b) following addition of dithionite to 14.; (c) 4 h; (d) following addition of authentic 1 to reaction mixture shown in c.