Skip to main content
. Author manuscript; available in PMC: 2012 Oct 13.
Published in final edited form as: J Med Chem. 2011 Sep 9;54(19):6647–6656. doi: 10.1021/jm200521a

Figure 6.

Figure 6

Effect of clodronate prodrug 15 on cell cycle, determined using the PI and FACS analysis. A) A549 cells treated with 0, 3, and 10 µM of 15 for 72 h. B) A549 cells treated with 0, 3, and 10 µM of 15 for 72 h and nocodazole for the final 24h. In the nocodazole-treated cells, accumulation of cells in G1 phase is evident at 3 and 10 µM of 15.