Table 1.
Total (N1 = 2099) | Women (N = 1297) | Men (N = 802) | |
---|---|---|---|
BDNF concentrations | |||
Serum BDNF, ng/ml | 14 (3.0) | 14.2 (3.0) | 13.8 (3.1) |
Plasma BDNF, pg/ml | 247.4 (191.6) | 258.2 (194.8) | 226.5 (183.9) |
Depression measures | |||
CES-D | 12.3 (7.9) | 13.7 (8.5) | 10.0 (6.1) |
CES-D ≥ 20 | 324 (15.9%) | 267 (21.1%) | 57 (7.4%) |
CES-D ≥ 28 | 114 (5.6%) | 101 (8%) | 13 (1.7%) |
Neuroticism | 56.0 (9.5) | 58.1 (9.7) | 52.5 (8.0) |
Anxiety | 56.7 (9.2) | 58.6 (9.3) | 53.4 (8.1) |
Angry Hostility | 53.2 (9.3) | 53.5 (9.6) | 52.7 (8.8) |
Depression | 53.4 (9.6) | 54.9 (10.1) | 51.0 (8.0) |
Self-Consciousness | 51.8 (10.0) | 53.1 (10.3) | 49.7 (9.1) |
Impulsiveness | 46.9 (9.2) | 47.1 (9.2) | 46.6 (9.2) |
Vulnerability | 56.1 (10.7) | 58.2 (10.9) | 52.6 (9.3) |
Covariates | |||
Age | 51.4 (15.3) | 50.8 (15.2) | 52.5 (15.4) |
BMI | 26.1 (4.6) | 25.4 (5.0) | 27.4 (3.8) |
BMI ≥ 30 | 382 (18.2%) | 207 (16%) | 175 (21.8%) |
Current smoker | 15% | 12% | 20% |
Ever smoker | 38% | 25% | 61% |
SSRI use | 2% | 2% | 1% |
N = 482 for plasma; N = 2037 for CES-D and for NEO-PI-R. The reported data are means with SD in parenthesis, or counts with percentages if followed by the % sign.
Abbreviations: BDNF, Brain-derived neurotrophic factor; BMI, body mass index (calculated as weight in kilograms divided by height in meters squared); CES-D, Center for Epidemiological Studies Depression Scale; SSRI = Selective Serotonin Reuptake Inhibitor.