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. 2001 Apr 10;98(8):4646–4651. doi: 10.1073/pnas.081141998

Figure 6.

Figure 6

Up-regulation of c-MYC promoter in p300-depleted cells. (A) Diagram of the TBE1/2 (wild-type MYC) and TBE1 m/2 m in which two TCF-4-binding sites are mutated (20). (B) Time course of promoter–reporter assay. MCF 10A cells were transfected (TX) with appropriate reporter plasmids, serum starved, and infected with Ad vectors before being harvested for luciferase assay as shown. (C) MYC promoter-reporter activity in p300-depleted cells. Cells harvested after transfection and infection as described in B were assayed for luciferase activity. Average values of three experiments with error bars are shown.