Table 1.
The number and mean duration of episodes from the different sleep states to wakefulness are shown for the light and dark phases (expressed as mean value per period of 12-h).
| SHAM | SNI | ||||
|---|---|---|---|---|---|
| Baseline (n = 6) | Surgery (n = 6) | Baseline (n = 6) | Surgery (n = 6) | ||
| EPISODE | |||||
| WK | Light | 256.3 (23.4) | 303.7 (29.2) # | 291.1 (19.7) | 383.7 (22.1)* |
| Dark | 314.1 (15.2) | 312.9 (20.9) # | 310.3 (13.3) | 491.9 (31.7)* | |
| SWS | Light | 207.8 (12.3) | 199.1 (23.3) | 195.5 (14.2) | 177.3 (24.3) |
| Dark | 232.7 (14.2) | 254.1 (23.4) # | 241.8 (26.2) | 376.5 (28.1)* | |
| REM | Light | 37.1 (7.2) | 23.4 (7.2) | 38.3 (6.0) | 22.1 (7.2) |
| Dark | 56.3 (11.0) | 58.0 (3.2) | 59.1 (11.2) | 68.2 (21.2) | |
| WT | Light | 26.0 (9.8) | 15.8 (3.4) | 23.4 (9.9) | 18.8 (3.3) |
| Dark | 19.5 (5.4) | 18.2 (3.7) | 18.3 (5.7) | 17.8 (3.1) | |
| M | Light | 11.4 (4.3) | 6.7 (2.1) | 13.6 (4.5) | 6.8 (2.1) |
| Dark | 21.1 (2.4) | 13.9 (0.9) | 20.8 (3.7) | 17.7 (3.4) | |
| U | Light | 282.2 (25.9) | 286.3 (26.9) # | 258.2 (24.9) | 398.6 (16.9)* |
| Dark | 315.9 (33.7) | 312.3 (40.2) # | 318.4 (22.5) | 502.9 (23.2)* | |
| DURATION (S) | |||||
| WK | Light | 66.4 (15.1) | 59.1 (17.9) | 61.1 (14.1) | 58.4 (15.7) |
| Dark | 61.1 (24.6) | 59.9 (15.6) | 64.9 (17.1) | 44.9 (8.9) | |
| SWS | Light | 68.8 (26.5) | 66.1 (26.6) | 65.2 (12.5) | 74.3 (16.2) |
| Dark | 47.3 (23.5) | 51.2 (24.5) | 49.9 (15.1) | 35.4 (9.8) | |
| REM | Light | 34.3 (13.2) | 27.6 (14.4) | 29.2 (9.8) | 31.3 (11.2) |
| Dark | 31.0 (5.7) | 28.1 (8.8) | 23.1 (8.8) | 26.2 (10.0) | |
| WT | Light | 6.8 (3.9) | 4.0 (2.9) | 3.3 (0.5) | 5.8 (1.7) |
| Dark | 5.5 (3.7) | 5.4 (1.1) | 4.3 (0.9) | 2.9 (0.3) | |
| M | Light | 15.2 (10.7) | 9.3 (4.8) | 10.7 (6.1) | 5.7 (2.1) |
| Dark | 7.9 (2.6) | 5.2 (2.7) | 6.8 (2.4) | 7.4 (1.8) | |
| U | Light | 23.5 (2.9) | 27.8 (5.6) # | 25.4 (2.4) | 11.6 (1.3)* |
| Dark | 27.9 (3.4) | 28.4 (7.9) # | 23.4 (4.2) | 8.3 (1.6)* | |
Six different brain states were considered: WK, waking state; SWS, slow-wave-sleep; REM, rapid-eye-movement sleep; WT, whisker-twitching; M, undefined movement; U, transition state. Values are expressed as mean (SEM). Statistical differences between study groups indicated by asterisks (*) for SNI-baseline/SNI-surgery and cardinal (#) for SHAM-surgery/SNI-surgery comparisons (*/# P < 0.05).