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Estimated time constants for recovery of Nav1.7 channels from 10 s pulses in the absence and presence of lidocaine
| Pre-pulse voltage (mV) | No lidocaine | 1 mM lidocaine | |||||
|---|---|---|---|---|---|---|---|
| Tau 1 (ms) | A1 | Tau 2 (ms) | A2 | Tau 3 (s) | A3 | Tau (ms) | |
| −100 mV | 4.63 ± 1.6 | 0.14 | 1046 ± 300 | 0.11 | N/A | N/A | 220 ± 16 |
| −50 mV | 6.64 ± 0.9 | 0.44 | 207 ± 37 | 0.44 | 4.3 ± 3.0 | 0.10 | 129 ± 5.0 |
| 0 mV | 6.22 ± 4.3 | 0.21 | 245 ± 26 | 0.61 | 4.9 ± 1.4 | 0.18 | 189 ± 12 |
Values are mean ± SEM.
N/A, not applicable.
