Figure 1.

Western blot showing hERG 1a and 1b protein stably expressed in HEK-293 cells and visualized with a C-terminal pan-hERG antibody (Novus Biologicals, Littleton, CO, USA). From the top, the signals represent mature (Golgi-glycosylated) hERG 1a at 155 kDa, immature (ER-resident) 1a at 135 kDa (Zhou et al., 1998), mature hERG 1b at 95 kDa, and immature 1b at 85 kDa (Jones et al., 2004).