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. 2011 Sep;164(2b):551–560. doi: 10.1111/j.1476-5381.2011.01473.x

Figure 6.

Figure 6

Endothelial dysfunction in 5/6 NX rats and the effect of VS-105. Sham and 5/6 NX rats were treated with vehicle or VS-105 at indicated doses as described in Figure 3. Vascular function was determined as described in Methods (n = 7–10 per group). (A) Acetylcholine-evoked relaxation. (B) SNP-evoked relaxation. Group mean ± SEM are presented. Statistical analysis was determined using a two-way anova, followed by a Bonferroni post hoc test. *P < 0.05, **P < 0.01, ***P < 0.001 versus vehicle.