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Dissociation rate constants for the radioligands [3H]-prazosin (α1A), [3H]-MK-912 (α2A) and [3H]-NMS (M4)
| [3H]-Ligand dissociation rate (min−1) | |||
|---|---|---|---|
| Receptor | Control | 30 nM MT3 | 300 nM MT3 |
| α1A | 0.0400 ± 0.0024 | 0.0441 ± 0.0024 | 0.0403 ± 0.0050 |
| α2A | 0.0264 ± 0.0024 | 0.0273 ± 0.0026 | 0.0328 ± 0.0089 |
| M4 | 0.0271 ± 0.0054 | 0.0268 ± 0.0051 | 0.0287 ± 0.0068 |
Data are given as means ± SD from two experiments.
