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. 2011 Sep;164(2b):538–550. doi: 10.1111/j.1476-5381.2011.01468.x

Table 3.

Dissociation rate constants for the radioligands [3H]-prazosin (α1A), [3H]-MK-912 (α2A) and [3H]-NMS (M4)

[3H]-Ligand dissociation rate (min−1)
Receptor Control 30 nM MT3 300 nM MT3
α1A 0.0400 ± 0.0024 0.0441 ± 0.0024 0.0403 ± 0.0050
α2A 0.0264 ± 0.0024 0.0273 ± 0.0026 0.0328 ± 0.0089
M4 0.0271 ± 0.0054 0.0268 ± 0.0051 0.0287 ± 0.0068

Data are given as means ± SD from two experiments.