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. 2011 Jul 19;105(5):628–639. doi: 10.1038/bjc.2011.240

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Copyright © 2011 Cancer Research UK

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Summary of the components of a robust preclinical evaluation package for a putative targeted radiosensitiser. Abbreviations: Ki=dissociation constant; GEMMs=genetically engineered mouse models; siRNA=small interfering ribonucleic acid; shRNA=short hairpin ribonucleic acid; MTT=(dimethylthiazol-2-yl)-2,5diphenyltetrazolium bromide; SRB=sulforhodamine B; MTS=3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2H-tetrazolium.