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The effect of pyrimethamine in an adult PKD model
| Number of animals | Body weight (g) | Kidney weight (mg) | K/BW ratio (mg/g) | Cyst number | |
|---|---|---|---|---|---|
| Vehicle | 4 (2 m, 2 f) | 24.9 ± 1.5 | 217.6 ± 27.8 | 8.7 ± 1.0 | 426 ± 166 |
| Pyrimethamine | 4 (2 m, 2 f) | 26.2 ± 2.2 | 177.6 ± 15.1 | 6.8 ± 0.5 | 197 ± 4 |
| P-value | NS | P< 0.023 | P< 0.007 | P< 0.038 |
m, male; f, female.
