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Kaplan-Meier estimates of overall survival in (A) all patients (n = 288; reprinted with permission31) and (B) patients split by combination of insulin-like growth factor-1 (IGF-1) and vascular endothelial growth factor (VEGF) levels. HH, high VEGF, high IGF-1; HL, high VEGF, low IGF-1; LH, low VEGF, high IGF-1; LL, low VEGF, low IGF-1.
