Table 1.
Densities of rod and cone photoreceptors in control and RA-treated embryos, and in theoretical datasets
Cell densities (cells/3600 μm2) | ||||
---|---|---|---|---|
60 hpf | 75 hpf | |||
Cell Type | Control | RA | Control | RA |
Rods | 9.56 ± 2.55 | 19.2 ± 6.75** | 16.2 ± 2.68 | N.D.a |
Cones: | ||||
Red | 70.5 ± 12.69 | 53.33 ± 13.42* | 59.50 ± 8.23 | 28.40 +8.53*** |
Blue | 45.44 ± 5.66 | 37.1 ± 8.30* | 52.56 ± 18.56 | 38.33 ± 10.71* |
UV | 47.33 ± 6.96 | 40.11 ± 5.80* | N.D. | N.D |
Theoretical red cone loss (n = 5)b | ||||
25% loss | 50% loss | 25% loss | 50% loss | |
48.4 ± 10.81** | 32.40 ± 7.5*** | 43.20 ± 7.53** | 29.40 ± 5.81*** |
*p < 0.05; **p < 0.01; ***p < 0.001 (Student's t-test).
N.D. = Not done.
a Rod density was so high as to preclude accurate counting.
b As compared to red cone density at 75 hpf.