Table 5. Local and systemic Adverse Events in Group 1 and Group 2.

Sign or Symptom	Group 1 N = 6 CSP+AMA1 low dose		Group 2 N = 6 CSP+AMA1 high dose
	All	Gr 3	All	Gr 3
LOCAL
Pain/Tenderness	5 (83)	0	5(83)	0
Erythema	0	0	0	0
Induration/Swelling	0	0	1(17)	0
Warmth	0	0	1(17)	0
Hives	0	0	0	0
Lymphadenopathy	2(33)*	0	0	0
Limited arm motion	1(17)*	0	0	0
MEAN† LOCAL	1.3		1.2
SYSTEMIC
Headache	2(33)	0	3(50)	1(17)
Malaise	1(17)	0	4(67)	0
Fever (objective)	0	0	2(33)‡	0
Fever (subjective)	1 (17)	0	2(33)	0
Chills	0	0	4(67)	1(17) §
Myalgia	2(33)	0	2(33)	1(17)
Arthralgia	1(17)	0	1(17)	0
Nausea/vomiting	2(33)	0	3(50)	0
Diarrhea	0	0	1(17)	0
Blurred vision	0	0	1(17)	0
Dizziness	0	0	1(17)	0
MEAN† SYSTEMIC	1.5		4.0	0.5

Gr = severity grade.

*ipsilateral axillary tenderness.