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. 2011 Oct 7;6(10):e26052. doi: 10.1371/journal.pone.0026052

Figure 3. Testis specific genes are commonly methylated in somatic lineages.

Figure 3

a) Overview of DNA methylation profiling b) Methylation of germline-specific genes in somatic lineages. A green line indicates a CpG island region. c) Gene Set Enrichment Analysis (GSEA) determines whether a defined set of genes shows concordant changes between two biological states. The normalized enrichment score (NES) reflects the degree to which a gene set is upregulated (positive NES). Corresponding p values are indicated.