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. 2011 Oct 7;6(10):e25932. doi: 10.1371/journal.pone.0025932

Table 2. Results of 10 mg/kg PTZ screen.

Mean (±SEM) p-Value N
Wildtype Pum2XE772
10 mg/kg
Event count after 1st injection 0.5±0.38 21.5±9.07 0.0052 ** 8; 8
Event count after 2nd injection 9.63±3.25 46.25±10.97 0.0054 ** 8; 8
45 mg/kg
Time until 1st event (s) 159.9±42.67 70.00±13.88 0.0403 * 8; 8
Time until seizure (s) 558.6±124.4 265.5±82.73 0.065 8; 8
Time: 1st spike – seizure (s) 398.8±92.16 195.5±71.68 0.03 * 8; 8
Duration of seizure (behavioral events, s) 18.72±1.91 45.12±4.8 0.0079 ** 5; 5
Event count after seizure (3 h) 57.00±23.48 147.9±36.74 0.0289 * 8; 7

*p<0.05;

**p<0.01.