Table 1.
Characteristics of 833 Men with Prostate Cancer Overall and Stratified by Race/Ethnicity and Quartile of Census Tract-Level Concentrated Disadvantage at Diagnosis: 4 Chicago-Area Medical Centers, 1986–1990
| Race/Ethnicity | Census Tract-Level Concentrated Disadvantage Score | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Characteristic | Overall (n=833) |
White, Non- Hispanic (n=513) |
African- American (n=320) |
pa,b | Lowest 1st Quartile |
2nd Quartile |
3rd Quartile |
Highest 4th Quartile |
pb,c |
| Follow-up time, y, Mean (SD) | 8.6 (6.9) | 9.4 (6.9) | 7.4 (6.5) | <.0001 | 10.7 (7.1) | 8.6 (7.0) | 7.4 (6.3) | 7.6 (6.6) | <.0001 |
| Deaths, N (%) | |||||||||
| Any cause | 622 (75.5) | 349 (70.0) | 268 (83.8) | <.0001 | 126 (60.3) | 152 (73.1) | 174 (83.7) | 175 (84.1) | <.0001 |
| Prostate cancer | 256 (30.7) | 140 (27.3) | 116 (36.3) | .0064 | 55 (26.3) | 61 (29.3) | 67 (32.2) | 75 (35.1)d | .24 |
| African-American, N (%) | 320 (38.4) | n/a | n/a | 8 (3.4) | 20 (9.6) | 111 (53.4) | 181 (87.0) | <.0001 | |
| Age at diagnosis, y, Mean (SD) | 69.0 (7.8) | 68.8 (7.8) | 69.3 (7.8) | .29 | 68.8 (8.1) | 68.5 (7.6) | 69.5 (7.8) | 69.1 (7.8) | .56 |
| Charlson Comorbidity Score, Mean (SD) | 1.8 (2.1) | 1.6 (2.0) | 2.2 (1.7) | .0017 | 1.2 (1.7) | 1.6 (1.9) | 2.3 (2.3) | 2.0 (2.2) | <.0001 |
| Stage, N (%) | |||||||||
| Distant/Unknown | 419 (50.3) | 226 (44) | 193 (60.3) | <.0001 | 98 (46.9) | 91 (43.8) | 105 (50.5) | 125 (60.1) | .0058 |
| Differentiation, N (%) | |||||||||
| Well | 187 (22.4) | 126 (24.6) | 61 (19.1) | 45 (21.5) | 52 (25.0) | 45 (21.6) | 45 (21.6) | ||
| Moderate | 314 (37.7) | 194 (37.8) | 120 (37.5) | 77 (36.8) | 80 (38.5) | 75 (36.1) | 82 (39.4) | ||
| Poor | 332 (39.9) | 193 (37.6) | 139 (43.4) | .114 | 87 (41.6) | 76 (36.5) | 88 (42.3) | 81 (38.9) | .89 |
| 1st-Course Treatment(s), N (%) | |||||||||
| Surgery | 260 (31.2) | 180 (35.1) | 80 (25.0) | .0022 | 79 (37.8) | 70 (33.7) | 52 (25.0) | 59 (28.3) | .0253 |
| Radiation | 279 (33.5) | 201 (39.2) | 78 (24.4) | <.0001 | 86 (41.2) | 81 (38.9) | 67 (32.2) | 45 (21.6) | <.0001 |
| Castration | 203 (24.4) | 112 (21.8) | 91 (28.4) | .031 | 46 (22.0) | 48 (23.1) | 49 (23.6) | 60 (28.9) | .37 |
| Diethylstilbesterol | 37 (4.4) | 19 (3.7) | 18 (5.6) | .19 | 6 (2.9) | 11 (5.3) | 12 (5.8) | 8 (3.9) | .45 |
| Observation only | 55 (6.6) | 25 (4.9) | 30 (9.4) | .011 | 9 (4.3) | 11 (5.3) | 15 (7.2) | 20 (9.6) | .14 |
| Experimental | 57 (6.8) | 21 (4.1) | 36 (11.3) | <.0001 | 10 (4.8) | 6 (2.9) | 15 (7.2) | 26 (12.5) | .0007 |
| Healthcare Setting, N (%) | |||||||||
| Private sector | 456 (54.7) | 342 (66.7) | 144 (35.6) | 171 (81.8) | 127 (61.1) | 98 (47.1) | 60 (28.9) | ||
| VHA | 377 (45.3) | 171 (33.3) | 206 (64.4) | <.0001 | 38 (18.2) | 81 (39.9) | 110 (52.9) | 148 (71.1) | <.0001 |
| Census Tract-Level | 98 (32.9) | 80.8 (21.3) | 124.4 (30.3) | <.0001 | |||||
| Concentrated Disadvantage Score, Mean (SD) [range] | [37.2 to 235.7] | [37.2 to 205.0] | [52.8 to 235.7] | ||||||
Note: SD = standard deviation; VHA = Veterans Health Administration
a
t-test for continuous variables
b
Chi-square test for categorical variables
c
Analysis of Variance for continuous variables
d
Versus 1st quartile, p = .052