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. Author manuscript; available in PMC: 2012 Oct 1.
Published in final edited form as: Cancer Epidemiol Biomarkers Prev. 2011 Aug 22;20(10):2237–2249. doi: 10.1158/1055-9965.EPI-11-0548

Figure 6. Relationship between histopathology scores and cagA upstream sequences.

Figure 6

DNA sequencing revealed 4 regions upstream of the cagA ATG initiation site that varied among the different Colombian strains (see Figure 2A). The strains vary in the number of copies of the indicated DNA sequences (Panels A, B, C) or vary in -10 sequences (Panel D). The histology scores are compared with the number of AATAAGATA motifs (Panel A), TGGATC motifs (Panel B), TAATGA motifs (Panel C), and type of -10 sequence (Panel D). p-values were calculated using t-test (Panels A, B, C) or one-way analysis of variance (Panel D).