TABLE 3.
Variable | Vehicle | BAM 8–22, μg/kg
|
---|---|---|
30 | ||
Number of rats | 4 | 6 |
Mean ± SE | ||
ICI, mins | ||
before treatment | 16.6 ± 1.95 | 16.7 ± 1.93 |
after treatment | 16.8 ± 1.63 | 23.0 ± 5.26*†† |
BP, cmH2O | ||
before treatment | 4.03 ± 1.13 | 4.32 ± 0.91 |
after treatment | 4.03 ± 1.10 | 4.47 ± 0.95 |
PT, cmH2O | ||
before treatment | 11.3 ± 1.71 | 11.5 ± 1.47 |
after treatment | 11.0 ± 1.62 | 22.9 ± 2.06*† |
MVP, cmH2O | ||
before treatment | 24.6 ± 4.78 | 25.2 ± 4.27 |
after treatment | 24.9 ± 4.48 | 32.3 ± 4.47**†† |
PVR, ml | ||
before treatment | 0.10 ± 0.02 | 0.10 ± 0.01 |
after treatment | 0.10 ± 0.03 | 0.11 ± 0.02 |
P <0.01,
P <0.05 (paired t-test);
P <0.01,
P<0.05 vs vehicle injection (Dunnett’s multiple comparison test)