TABLE 4.
Variable | Vehicle | BAM 8–22, μg
|
---|---|---|
0.3 | ||
Number of rats | 4 | 6 |
Mean ± SE | ||
ICI, mins | ||
before treatment | 15.3 ± 2.25 | 15.7 ± 1.89 |
after treatment | 15.3 ± 3.08 | 23.5 ± 3.45*† |
BP, cmH2O | ||
before treatment | 2.83 ± 1.42 | 3.17 ± 1.29 |
after treatment | 2.84 ± 1.36 | 3.26 ± 1.18 |
PT, cmH2O | ||
before treatment | 7.99 ± 2.28 | 7.95 ± 1.72 |
after treatment | 7.97 ± 2.21 | 15.95 ± 1.75*† |
MVP, cmH2O | ||
before treatment | 21.8 ± 2.18 | 22.3 ± 1.36 |
after treatment | 22.1 ± 2.64 | 26.2 ± 1.73*† |
PVR, ml | ||
before treatment | 0.10 ± 0.02 | 0.10 ± 0.01 |
after treatment | 0.09 ± 0.01 | 0.10 ± 0.02 |
P <0.01 (paired t-test);
P <0.01 vs vehicle injection (Dunnett’s multiple comparison test)