Table 2.

One-way sensitivity analyses for addition of radiation therapy in women age 60

			Invasive disease-free survival	Overall survival	Percentage with both breasts during lifetime
Baseline Δ			11.7 months	2.1 months	-8.6%
Variable	Baseline	Range Studied	Δ of Range (months)	Δ of Range (months)	Δ of Range (%)
Local recurrence at 10-years	0.2495	0.15 - 0.35	7.0 - 16.7	1.3 – 3.0	-7.6 to -9.6
Reduction in local recurrence with RT	0.46	0.30 - 0.70	8.0 – 17.4	1.4 – 3.1	-11.6 to -4.1
Proportion of invasive LR	0.50	0.30 - 0.70	9.0 - 15.9	1.4 - 2.9	-9.0 to -8.2
Proportion of invasive new cancer	0.69	0.30 - 0.80	11.2 - 11.9	2.1 - 2.2	-9.0 to -8.5
Contralateral-breast cancer/yr	0.008	0.004 - 0.010	12.1 – 11.6	2.1 – 2.2	-10.0 to -8.1
Proportion mastectomy at recurrence or new cancer if no prior RT	0.32*	0.20 – 0.48	11.7-11.5	2.1 – 2.1	-11.7 to -4.3

RT = radiation therapy

LR = local recurrence

Δ = difference with the addition of radiation therapy

^*= in baseline analysis, this variable is a function of the stage of recurrence or new diagnosis; on average it is 0.32