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. Author manuscript; available in PMC: 2012 Oct 15.
Published in final edited form as: J Immunol. 2011 Sep 9;187(8):4161–4169. doi: 10.4049/jimmunol.1101731

Figure 3. T-PPAR CD4+ T cells are defective in accumulating in the SPL, MLN, or cLP.

Figure 3

Splenic CD4+CD25− Teff were purified from littermate or T-PPAR mice by magnetic bead purification. 1 × 106 Teff/mouse were injected i.p. into RAG-1−/− mice. On day 7, 14, and 56 post-injection, SPL and MLN were harvested, counted and stained for CD4+MHCII− cells. A) The total number of CD4+MHCII− T cells recovered in the SPL and MLN at days 7, 14, and 56 are normalized, with littermate Teff set at 100% in each individual experiment. B) The total number of CD4+MHCII− T cells recovered in the cLP at day 14 are normalized, with littermate Teff set at 100% in each individual experiment. Results of CD4+ T cell recovery in (A) and (B) are depicted as mean % of littermate Teff. For A, day 7, n=7; day 14, n=9; day 56, n=6. For B: n=5. Error bars shown as s.e.m. *, p<0.05; **, p<0.01; ***, p<0.001.