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Potential sources of de novo β-cells among differentiated adult MSC: BM: bone marrow, AT: adipose tissue; UCB: umbilical cord blood.
| Rodent | Human | |||
|---|---|---|---|---|
| in vitro | in vivo | in vitro | in vivo | |
| Pancreatic | ||||
| Islet-(derived) MSC | ? | ? | + | ? |
| Exocrine-(derived) MSC | ? | ? | −/+ | ? |
|
| ||||
| Extra-pancreatic | ||||
| BM-MSC AT-MSC UCB-MSC |
+ | −/+ | −/+ | − |
