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. 2011 Aug 26;12(9):5471–5489. doi: 10.3390/ijms12095471

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© 2011 by the authors; licensee MDPI, Basel, Switzerland.

This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).

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Effect of different 4-oxo-flavonoids of 40 μM on oxLDL-induced endothelial viability (A) and the level of MDA (B), NO (C) and sICAM-1 (D). EA.hy926 cells were pretreated with different 4-oxo-flavonoids of 40 μM, and exposed to oxLDL of 100 μg/mL for another 24 hs. Cell viability was measured by CCK-8 assay and the values were determined as the percentage of the control group. The level of MDA, NO, and sICAM-1 were determined by the corresponding detecting kits. All of the data are expressed as the means ± S.D. ^# P < 0.05, ^## P < 0.01, compared with the control group; * P < 0.05, ** P < 0.01, compared with the oxLDL group.