Table 1.
Biochemical profile of hypercholesterolemic individuals in response to atorvastatin (10 mg/day/4 weeks).
| Variables | Basal | Atorvastatin * | Change (%) | P |
|---|---|---|---|---|
| TC (mg/dL) | 281 ± 38 | 198 ± 30 | −28.9 ± 9.5 | <0.001 |
| LDL-C (mg/dL) | 193 ± 55 | 118 ± 27 | −38.3 ± 12.4 | <0.001 |
| HDL-C (mg/dL) | 56 ± 14 | 54 ± 13 | −2.5 ± 10.5 | <0.002 |
| TG (mg/dL) | 160 ± 66 | 132 ± 52 | −26.9 ± 52.5 | <0.001 |
| CK (U/L) | 102 ± 80 | 104 ± 88 | 4.9 ± 36.5 | 0.606 |
| ALT (U/L) | 22 ± 10 | 25 ± 15 | 23.0 ± 63.2 | <0.001 |
| ApoAI (g/L) | 130 ± 25 | 136 ± 27 | 4.9 ± 15.4 | 0.013 |
| ApoB (g/L) | 140 ± 22 | 102 ± 22 | −28 ± 46.1 | <0.001 |
TC: total cholesterol, LDL-C: low-density lipoprotein cholesterol; HDL-C: high-density lipoprotein cholesterol; TG: triglyceride; CK: Creatine kinase; ALT: Alanine aminotransferase; ApoAI: Apolipoprotein AI; ApoB: Apolipoprotein B.
*
10mg/daily for 4 weeks.