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Genetic background modifies severity of hearing impairment in Pou1f1dw/dw mice. Average 16-kHz ABR thresholds (with standard error bars) are shown for mice with different Pou1f1 genotypes on different strain backgrounds. Note that dwarf mutant mice on the DW/J and C57BL/6J strain backgrounds have a much more severe hearing impairment than mutant mice on the C3H/HeJ background (dB SPL = decibel sound pressure level).
