Table 1.
Baseline main clinical and demographic characteristics of HIV-infected patients based on rs10892151 genotype
| Characteristics at study entry | G/G carriers (n = 190) |
A/G carriers (n = 18) |
|---|---|---|
| Age, years | 39.1 (6.9) | 37.9 (7.0) |
| Gender, n (%) | ||
| Male | 127 (66.8) | 13 (72.2) |
| Female | 63 (33.2) | 5 (27.8) |
| BMI, kg/m2 | 22.74 (2.9) | 23.23 (3.6) |
| Risk factors for HIV, n (%) | ||
| Intravenous drug use | 114 (60.0) | 11 (61.1) |
| Heterosexual contact | 57 (30.0) | 5 (27.7) |
| Male homosexual contact | 19 (10.0) | 2 (11.2) |
| HCV co-infection, n (%) | 115 (60.5) | 13 (72.2) |
| HIV-1 RNA viral load, copies/mL | 246582 (776921) | 336652 (863524) |
| CD4+ T cell count, cells/μL | 448.9 (285.9) | 435.1 (290.9) |
| Treatment scheme, n (%) | ||
| NNRTI based | 103 (54.2) | 10 (55.5) |
| PI based | 87 (45.8) | 8 (44.5) |
| Apo C-III, μg/mL | 11.27 (4.9) | 10.42 (4.7) |
| Total cholesterol, mmol/L | 4.89 (1.2) | 4.80 (1.2) |
| HDL-cholesterol, mmol/L | 1.06 (0.4) | 1.08 (0.4) |
| VLDL-cholesterol, mmol/L | 0.87 (0.3) | 0.64 (0.2) |
| LDL-cholesterol, mmol/L | 2.91 (0.9) | 2.88 (0.9) |
| Triglycerides, mmol/L | 2.48 (2.0) | 2.40 (2.0) |
| Glucose, mmol/L | 5.39 (0.9) | 5.51 (1.0) |
| CRP, mg/L | 4.13 (5.4) | 4.91 (6.2) |
| MCP-1, pg/mL | 74.72 (41.8) | 81.17 (43.1) |
Values are the mean and the standard deviation (SD), unless otherwise indicated. BMI, body-mass index