Table 1.
Groups | No. of animals with fever (≥ 40.5°C) | No. of days to fever onset | Fever frequency during the trial | Survival rates |
---|---|---|---|---|
A | 5/5 | 2 | 26/56 | 0/5 |
B | 5/5 | 2 | 21/51 | 0/5 |
C | 5/5 | 3 | 18/58 | 0/5 |
D | 3/3 | 10 | 3/11 | 2/3 |
E | 0/2 | - | 0/30 | 2/2 |
Twenty specific-pathogen-free Bama miniature pigs were randomly divided into five groups. Groups A, B and C (n = 5) were inoculated i.m. with 104, 105 and 106 TCID50 CSFV Shimen strain, respectively. Three non-inoculated pigs were housed in the same pen and served as in-contact animals. Two uninfected control pigs were housed in a separate pen. Clinical outcome, fever frequency and survival rates after viral challenge were calculated.