Table 2. Resting and Post-Exercise Vessel Hemodynamic Parameters - Non-Smokers vs. Chronic Smoking.
P Values | |||||||||||
Resting | 2 min | 5 min | 10 min | 15 min | Resting | 2 min | 5 min | 10 min | 15 min | ||
HR | Non-S | 62.6±8.0 | 111.7±15.3& | 100.6±9.5& | 97.7±9.8& | 95.5±9.6& | NS | NS | 0.01 | 0.02 | 0.02 |
CS | 61.7±8.0 | 104.8±15.0& | 91.2±10.1& | 88.3±10.5& | 86.2±10.6& | ||||||
Aortic PP | Non-S | 27.0±4.7 | − | 41.1±12.7& | 31.0±9.7& | 27.6±7.0 | 0.04 | − | NS* | NS* | 0.02 |
CS | 23.9±6.5 | − | 35.0±5.8& | 26.9±4.3& | 22.0±4.6& | ||||||
MAP | Non-S | 82.2±8.9 | 94.1±12.5& | 81.4±10.7 | 80.3±8.9 | 81.7±8.9 | NS | NS | NS | 0.01 | 0.03 |
CS | 83.2±8.4 | 94.2±10.8& | 84.2±9.5 | 85.6±7.6 | 85.6±7.8 | ||||||
cfPWV | Non-S | 6.0±0.7 | 9.0±2.0& | 6.6±1.3& | 6.1±0.9 | 6.1±0.9 | NS | NS | NS | NS* | NS* |
CS | 6.3±1.0 | 8.8±1.7& | 7.1±1.4& | 6.7±1.0& | 6.7±1.1& | ||||||
AIx75 | Non-S | −11.4±10.0 | − | 12.9±7.5& | 6.6±8.2& | 3.2±9.2& | 0.04 | − | NS | 0.01 | 0.003 |
CS | −3.5±10.4 | − | 10.9±8.7& | 4.1±9.8& | −1.0±9.5 | ||||||
SEVR | Non-S | 173.4±44.8 | − | 75.6±24.9& | 80.7±26.4& | 87.0±24.8& | NS | − | NS* | NS* | 0.003 |
CS | 163.7±26.8 | − | 91.1±16.7& | 97.8±17.4& | 111.6±20.9& |
HR, heart rate (beats per minute); Non-S, non-smokers; CS, smokers-chronic smoking condition; PP, pulse pressure (mmHg); MAP, mean arterial pressure (mmHg); cfPWV, carotid-femoral pulse wave velocity (m/s); AIx75, augmentation index adjusted to heart rate of 75 beats per minute (%); SEVR, subendocardial viability ratio (%)
All values are mean±standard deviation.
P<0.05 before adjustment.
P<0.05 against resting value (i.e. this parameter has not recovered to resting levels).
Resting HR, cfPWV, AIx75, and SEVR are adjusted for age and resting MAP. Post-exercise, these variables are adjusted for age, exercise time, resting MAP, and the corresponding resting parameter.
Resting aortic PP and MAP were adjusted for age. Post-exercise, these variables were adjusted for age, exercise time, and the corresponding resting parameter.