Figure 2.

Virus-like particle (VLP) budding induced by deletion mutants at the N- and C-terminus of VP40. Schematic diagrams of the deletion mutants at A, the N- terminus, and C, the C-terminus of VP40. B, D, Comparison of VLP budding induced by the deletion mutants. We transfected 293T cells with a plasmid expressing each of the deletion mutants. At 48 h after transfection, the VLP budding assay was performed. Thirty-five amino acids at the N-terminus and 5 amino acids at the C-terminus of VP40 were dispensable for VLP budding.