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hnRNP C1/C2 binding to KPNA1 is inhibited by VP24. Cells were cotransfected with KPNA1 and either empty plasmid or increasing amounts of EBOV VP24 plasmid. Endogenous hnRNPC1/C2 binding to KPNA1 is partially blocked in the presence of VP24 as assessed by Western blot, as indicated (top). Whole cell extracts from A were analyzed by Western blot, as indicated; VP24 does not affect total levels of hnRNPC1/C2 (bottom).
