Figure 3.
Genome copies of Bundibugyo ebolavirus (BEBOV) in samples from BEBOV-challenged cynomolgus macaques. Blood (A), rectal (B), and throat (C) swab samples were obtained at the time point indicated, total RNA was extracted, quantitative real-time reverse-transcription polymerase chain reaction was performed, and genome copies were calculated. Survivors are indicated by a closed box, whereas animals that were euthanized due to clinical score are indicated by an open box. Data points along the x-axis represent surviving animals that did not have detectable viremia. (VSVΔG-ZEBOVgp), vesicular stomatitis virus lacking its glycoprotein gene, containing the Zaire ebolavirus glycoprotein; (VSVΔG-CIEBOVgp), vesicular stomatitis virus lacking its glycoprotein gene, containing the Côte d'Ivoire ebolavirus glycoprotein; DMEM, Dulbecco's modified Eagle medium.