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. Author manuscript; available in PMC: 2012 Dec 1.
Published in final edited form as: Biomaterials. 2011 Sep 28;32(35):9536–9545. doi: 10.1016/j.biomaterials.2011.08.069

Figure 5.

Figure 5

Transduction efficiency (A), cytotoxicity (B), and ratio of GFP positive mean fluorescence (C) of pHK10-Ad5 compared to Ad5 in three different CAR negative cell lines. Virus was used at MOI of 5, 50, and 1000 for CHO-K1, RAW, and BaF3 cells respectively. * pHK10-Ad5 showed statistically higher transduction compared to Ad5 in all cell types (p<0.05). There was no statistical difference in cell cytotoxicity between Ad5 and pHK10-Ad5 within each of the cell lines. pHK10-Ad5 showed significantly higher toxicity in BaF3 cells compared to RAW 264.7 and CHO-K1 cells (p<0.05).