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. Author manuscript; available in PMC: 2012 Nov 1.
Published in final edited form as: Bioorg Med Chem Lett. 2011 Aug 24;21(21):6451–6455. doi: 10.1016/j.bmcl.2011.08.084

Figure 3.

Figure 3

A) Structures of cyclic constrained analogs of 8. B) 10 µM M1 single point screen of cyclic constraint variants of ML071. C) Full CRCs at M1–M5 for VU0364572 (17).