Table 1.
Characteristics of HCC and control subjects
| Variable | Number of subjectsa |
Pb | |
| HCC cases (n=315) | Controls (n=356) | ||
| Age | |||
| ≤50 years | 143 (45.4%) | 167 (46.9%) | 0.70 |
| >50 years | 172 (54.6%) | 189 (53.1%) | |
| Sex | |||
| Female | 52 (16.5%) | 59 (16.6%) | 0.98 |
| Male | 263 (83.5%) | 297 (83.4%) | |
| Alcohol drinking | |||
| Never | 195 (61.9%) | 218 (61.2%) | 0.86 |
| Ever | 120 (38.1%) | 138 (38.8%) | |
| Cigarette smoking | |||
| Never | 171 (54.3%) | 206 (57.9%) | 0.35 |
| Ever | 144 (45.7%) | 150 (42.1%) | |
| HBsAg | |||
| Negative | 42 (13.3%) | 48 (13.5%) | 0.96 |
| Positive | 273 (86.7%) | 308 (86.5%) | |
| Anti-HCV | |||
| Negative | 298 (94.6%) | 350 (98.3%) | 0.01 |
| Positive | 17 (5.4%) | 6 (1.7%) | |
| HCC family historyc | |||
| No | 295 (93.7%) | 345 (96.9%) | 0.04 |
| Yes | 20 (6.3%) | 11 (3.1%) | |
| Tumor size | |||
| ≤5 cm | 155 (49.2%) | ||
| >5 cm | 160 (50.8%) | ||
| Edmondson-Steiner grade | |||
| I/II | 64 (20.3%) | ||
| III/IV | 251 (79.7%) | ||
| Tumor stage | |||
| I/II | 227 (72.1%) | ||
| III/IV | 88 (27.9%) | ||
a
Data are expressed as n (%)
b
χ 2-test
c
Family history of HCC in first-degree relatives