Fig. 3.

Effects of iptakalim on brain edema after cerebral I/R injury

Rats were treated with saline (sham operation) or received MCAO. Iptakalim (8 mg/kg BW) was administered to separate groups of rats that received MCAO at 1 h pre-ischemia, 1 h pre-reperfusion, 0, 1, 2, and 4 h post-reperfusion. Data are presented as the mean±SD (n=8). ^* P<0.05 for rats that received MCAO compared to the sham control group; ^# P<0.05 for rats that received MCAO plus iptakalim compared with rats that received MCAO plus saline