Table 2.
Breast density measurement associations
| Quartile OR (95% CI) | First (n1) | Second (n2) | Third (n3) | Fourth (n4) | Az |
|---|---|---|---|---|---|
| PD n=160 | 23 | 41 | 39 | 57 | |
| BMI adjusted | 1.00 (Ref.) | 2.50 (1.12, 5.56) | 2.85 (1.26, 6.45) | 4.94 (2.10, 11.62) | 0.630 |
| BMI, area adjusted | 1.00 (Ref.) | 2.57 (1.15, 5.75) | 2.87 (1.26, 6.53) | 5.17 (2.17, 12.33) | 0.637 |
| BMI, area, menopausal adjusted | 1.00 (Ref.) | 2.70 (1.19, 6.14) | 2.94 (1.27, 6.80) | 5.24 (2.18, 12.59) | 0.643 |
|
| |||||
| PGSD n=160 | 22 | 53 | 38 | 47 | |
| BMI adjusted | 1.00 (Ref.) | 3.36 (1.58, 7.13) | 2.89 (1.24, 6.74) | 4.84 (1.95, 12.02) | 0.637 |
| BMI, area adjusted | 1.00 (Ref.) | 3.80 (1.75, 8.24) | 3.56 (1.46, 8.69) | 6.18 (2.34, 16.28) | 0.639 |
| BMI, area menopausal adjusted | 1.00 (Ref.) | 4.63 (2.05, 10.47) | 4.26 (1.69, 10.76) | 7.43 (2.72, 20.28) | 0.651 |
|
| |||||
| RSD n=160 | 26 | 42 | 41 | 51 | |
| BMI adjusted | 1.00 (Ref.) | 1.81 (0.89, 3.67) | 2.11 (0.97, 4.61) | 2.78 (1.29, 5.97) | 0.617 |
| BMI, area adjusted | 1.00 (Ref.) | 2.07 (0.99, 4.30) | 2.59 (1.13, 5.94) | 3.48 (1.52, 7.93) | 0.625 |
| BMI, area menopausal adjusted | 1.00 (Ref.) | 2.17 (1.03, 4.57) | 2.86 (1.22, 6.72) | 3.76 (1.62, 8.70) | 0.634 |
|
| |||||
| RSDL n=160 | 21 | 39 | 44 | 56 | |
| BMI adjusted | 1.00 (Ref.) | 2.41 (1.15, 5.08) | 3.39 (1.52, 7.58) | 4.37 (1.94, 9.85) | 0.636 |
| BMI, area adjusted | 1.00 (Ref.) | 2.66 (1.24, 5.68) | 3.82 (1.67, 8.76) | 4.95 (2.14, 11.46) | 0.646 |
| BMI, area, menopausal adjusted | 1.00 (Ref.) | 2.89 (1.34, 6.27) | 4.44 (1.88, 10.49) | 5.38 (2.29, 12.63) | 0.654 |
|
| |||||
| RSDX n=160 | 24 | 55 | 36 | 45 | |
| BMI adjusted | 1.00 (Ref.) | 2.96 (1.44. 6.10) | 2.29 (1.06, 4.95) | 3.57 (1.48, 8.59) | 0.639 |
| BMI, area adjusted | 1.00 (Ref.) | 3.35 (1.58, 7.09) | 2.89 (1.26, 6.64) | 4.74 (1.81, 12.40) | 0.639 |
| BMI, area, menopausal adjusted | 1.00 (Ref.) | 3.50 (1.64, 7.47) | 3.11 (1.34, 7.23) | 4.87 (1.85, 12.84) | 0.650 |
This table gives the quartile odds ratio (OR) stratifications and area under the receiver operating characteristic curve (Az) quantities for each of the five breast density measures: (1) operator-assisted percentage of breast density (PD), (2) calibrated standard deviation (PGSD), (3) raw image standard deviation (RSD), (4) raw image standard deviation from the reduced breast area (RSDL), and (5) raw image standard deviation from the fixed box (RSDX). The number of cases in each stratification (n1–n4) is listed in the top row. The 95% confidence interval (CI) is provided parenthetically beneath each OR.