Blood collected from M290-SAP treated recipient bearing a long-term islet allograft (A), a normal age matched control (B), and islet allograft recipient undergoing unmodified rejection (C), was subjected to multicolor FACS analyses using mAbs to CD8, CD103, CD44, and CD62L. . Data shown are two-dimensional plots of the indicated markers by gated lymphocytes. Numbers in quadrants are percentages of total lymphocytes. Data are representative of at least three independent experiments.