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. Author manuscript; available in PMC: 2012 Jul 1.
Published in final edited form as: Chromosome Res. 2011 Jun 21;19(5):657–667. doi: 10.1007/s10577-011-9225-4

Fig. 6.

Fig. 6

Evolutionary perspective for the distribution of Sox2 and Sox14 among vertebrates. Rounds of whole genomic duplications, rearrangement and divergence from ancestral Sox B genes have originated the actual scenario observed. There is no data concerning linkage of Sox2 and Sox14 in poriferans and cnidarians, as well as in amphibians. For birds, the linkage of both genes was confirmed only in Gallus gallus. Among fish species Sox2 and Sox14 genes are not linked in zebrafish and both conditions (linkage and non-linkage) were detected among cichlids (present work). Both linkage and non-linkage of Sox2 and Sox14 genes were detected in several mammals (see Table 2 for details).