Table 1.
Placebo
|
Nicotine
|
|||
---|---|---|---|---|
Pre-gum | Post-gum | Pre-gum | Post-gum | |
Smokers (n = 11) | ||||
SYS | 114.2 ± 10.7 | 119.3 ± 10.6 | 118.3 ± 10.7 | 120.1 ± 11.6 |
DIAS | 69.3 ± 9.5 | 75.9 ± 5.8 | 74.7 ± 4.0 | 77.2 ± 8.1 |
Pulse | 72.0 ± 10.8 | 69.7 ± 9.4 | 74.2 ± 9.2 | 72.8 ± 10.7 |
Anxiety* | 38.0 ± 11.0 | —† | 39.9 ± 11.6 | —† |
SE‡ | 0.3 ± 0.5 | 0.5 ± 0.8 | 0.4 ± 0.5 | 0.3 ± 0.4 |
WD§ | 28.1 ± 18.7 | 31.6 ± 19.5 | 29.8 ± 16.2 | 26.3 ± 11.4 |
Ex-Smokers (n = 11) | ||||
SYS | 115.0 ± 10.7 | 118.4 ± 12.4 | 114.6 ± 10.7 | 113.9 ± 12.3 |
DIAS | 70.4 ± 7.3 | 72.4 ± 7.2 | 71.2 ± 5.9 | 70.0 ± 8.2 |
Pulse | 67.4 ± 8.3 | 66.4 ± 13.1 | 64.0 ± 11.2 | 65.9 ± 9.4 |
Anxiety | 23.7 ± 6.4 | —† | 24.5 ± 7.2 | —† |
SE | 0.3 ± 0.3 | 0.1 ± 0.2 | 0.1 ± 0.1 | 0.3 ± 0.5 |
WD | 3.6 ± 4.6 | 4.0 ± 4.0 | 3.7 ± 5.0 | 6.0 ± 4.7 |
SYS, systolic BP; DIAS, diastolic BP; SE, side effects; WD, withdrawal.
State trait anxiety index.
Not measured.
Subjective Treatment Emergent Symptom Scale.
Minnesota nicotine-withdrawal scale.