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. 2001 Mar 27;98(8):4728–4733. doi: 10.1073/pnas.061369098

Table 1.

Mean ± SD of physiological and self-report measures

Placebo
Nicotine
Pre-gum Post-gum Pre-gum Post-gum
Smokers (n = 11)
 SYS 114.2  ± 10.7 119.3  ± 10.6 118.3  ± 10.7 120.1  ± 11.6
 DIAS 69.3  ± 9.5 75.9  ± 5.8 74.7  ± 4.0 77.2  ± 8.1
 Pulse 72.0  ± 10.8 69.7  ± 9.4 74.2  ± 9.2 72.8  ± 10.7
 Anxiety* 38.0  ± 11.0 39.9  ± 11.6
 SE 0.3  ± 0.5 0.5  ± 0.8 0.4  ± 0.5 0.3  ± 0.4
 WD§ 28.1  ± 18.7 31.6  ± 19.5 29.8  ± 16.2 26.3  ± 11.4
Ex-Smokers (n = 11)
 SYS 115.0  ± 10.7 118.4  ± 12.4 114.6  ± 10.7 113.9  ± 12.3
 DIAS 70.4  ± 7.3 72.4  ± 7.2 71.2  ± 5.9 70.0  ± 8.2
 Pulse 67.4  ± 8.3 66.4  ± 13.1 64.0  ± 11.2 65.9  ± 9.4
 Anxiety 23.7  ± 6.4 24.5  ± 7.2
 SE 0.3  ± 0.3 0.1  ± 0.2 0.1  ± 0.1 0.3  ± 0.5
 WD 3.6  ± 4.6 4.0  ± 4.0 3.7  ± 5.0 6.0  ± 4.7

SYS, systolic BP; DIAS, diastolic BP; SE, side effects; WD, withdrawal. 

*

State trait anxiety index. 

Not measured. 

Subjective Treatment Emergent Symptom Scale. 

§

Minnesota nicotine-withdrawal scale.