Table 2.
Statistically significant brain regions for the interaction of temperament group uninhibited > inhibited) by face type (novel > familiar)
| Cluster |
Peak voxel |
|||||
|---|---|---|---|---|---|---|
| Brain regions (hemisphere) | Cluster Size | P-value | t-score | x | y | z |
| Frontal lobes | ||||||
| Lateral prefrontal cortex (L) | 2247 | <0.001 | 5.14 | –45 | 33 | 9 |
| Dorsolateral prefrontal cortex (R) | 149 | <0.001 | 3.79 | 30 | 42 | 15 |
| Inferior frontal gyrus (R) | 542 | <0.001 | 4.88 | 54 | 21 | 12 |
| Cerebellum and brainstem | ||||||
| Cerebellum dentate and declive (R) | 254 | <0.001 | 4.86 | 15 | –54 | –30 |
| Cerebellum dentate and culmen (L) | 222 | <0.001 | 3.85 | –12 | –48 | –33 |
| Cerebellum VIII and Crus I (L) | 80 | <0.001 | 4.04 | –24 | –60 | –39 |
| Brainstem (R/L) | 78 | <0.001 | 4.14 | 9 | –33 | –45 |
| Temporal lobes | ||||||
| Middle temporal gyrus (R) | 84 | <0.001 | 3.94 | 45 | –66 | 9 |
| Middle temporal gyrus (L) | 38 | <0.001 | 3.62 | –45 | –60 | 0 |
| Amygdala (L)a | 22 | 0.004 | 2.72 | –18 | –6 | –15 |
| Amygdala (R)a | 22 | 0.013 | 2.29 | 21 | 0 | –18 |
| Occipital lobes | ||||||
| Occipital cortex/BA19 (R) | 46 | <0.001 | 3.60 | 36 | –78 | 21 |
| Occipital cortex/BA19 (L) | 104 | <0.001 | 3.98 | –45 | –75 | 18 |
| Occipital cortex/BA18 (R) | 43 | 0.001 | 3.30 | 6 | –78 | –9 |
| Fusiform gyrus (R) | 27 | 0.001 | 3.34 | 39 | –36 | –27 |
| Calcarine sulcus/Precuneus (R) | 28 | 0.001 | 3.00 | 15 | –60 | 18 |
| Calcarine sulcus/Precuneus (L) | 80 | <0.001 | 3.90 | –6 | –69 | 21 |
| Sub-cortical regions | ||||||
| Insula (L) | 979 | <0.001 | 5.51 | –39 | 3 | 0 |
| Insula (R) | 45 | <0.001 | 4.08 | 36 | –3 | 12 |
| Caudate (R) | 52 | <0.001 | 4.64 | 18 | 18 | 3 |
| Thalamus (L) | 31 | <0.001 | 3.68 | –9 | –12 | 18 |
aSmall volume corrected.