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(A) Default-network connectivity for MDDs and HCs during fixation periods defined by connectivity with posterior-cingulate cortex, x = −7, y = −45, z = 24. Correlations >0.25 (P < 0.001) are displayed. (B) Results of a two-sample t-test comparing MDDs’ and HCs’ default-network connectivity during fixation periods. MDDs show more connectivity in the subgenual-cingulate than HCs (P < 0.05 corrected; peak at x = 0, y = 38, z = −9; 46 voxels).
