Table 1. Scandinavian MS case-control association analysis of KLRB1 SNP, rs4763655.
| Population | N | AA | AG | GG | RAF cases | RAF control | χ2 | P-value | OR (95% CI) |
|---|---|---|---|---|---|---|---|---|---|
| Norwegian | |||||||||
| Cases | 1903 | 224 | 866 | 813 | |||||
| Controls | 1540 | 178 | 702 | 660 | 0.35 | 0.34 | 0.023 | 0.88 | 1.01 (0.91–1.11) |
| Swedish | |||||||||
| Cases | 2246 | 273 | 1019 | 954 | |||||
| Controls | 1820 | 193 | 821 | 806 | 0.35 | 0.33 | 2.21 | 0.14 | 1.07 (0.98–1.18) |
| Danish | |||||||||
| Cases | 1218 | 159 | 584 | 475 | |||||
| Controls | 1125 | 141 | 490 | 494 | 0.37 | 0.34 | 3.76 | 0.053 | 1.13 (1.00–1.28) |
|
Combined analysis |
N |
AA |
AG |
GG |
|
|
χ2 |
P-value |
OR (95% CI) |
| Scandinavian combined | |||||||||
| Cases | 5367 | 654 | 2468 | 2245 | 3.978 | 0.046 | 1.06 (1.001–1.13) | ||
| Controls | 4485 | 512 | 2013 | 1960 | |||||
Abbreviations: OR, odds ratio; RAF, risk allele frequency.