Table 1.
Indications and contraindications for infliximab therapy in CD
Indications | Contraindications |
---|---|
Refractory luminal CD | Active abscess or infections |
Steroid-dependent CD | Suspected active tuberculosis |
Refractory fistulizing CD | Intestinal obstruction |
Systemic manifestations of IBD | Multiple sclerosis or optical neuritis |
Pyoderma gangrenosum | Previous lymphoma or neoplastic disease |
Chronic uveitis | Heart failure |
Abbreviations: CD, Crohn’s disease; IBD, inflammatory bowel disease.