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. Author manuscript; available in PMC: 2012 Sep 30.
Published in final edited form as: Cell. 2011 Sep 30;147(1):95–106. doi: 10.1016/j.cell.2011.07.048

Figure 6. Characterization of AID-dependent hotspots.

Figure 6

(A) Composite density graph showing the distribution of rearrangements in genes associated with AID-dependent hotspots relative to the TSS. (B) Spt5 and AID recruitment at genomic sites associated with translocation hotspots (Pavri et al., 2010; Yamane et al., 2011). (C) Somatic hypermutation frequency versus number of rearrangements in genes bearing AID-dependent translocation hotspots. (D) Distribution of AID, Spt5 and translocations in Rohema and Hist1 genes. Also see Figure S4.